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My nearest neighbours in idea-space appear to be Romano Prodi and the Dalai Lama. It seems like a nice quiet neighbourhood.
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So, is anyone out there even more centrist than me? I am keen to find out...
The line of comments is getting too long, so I thought I would pull things together again.
(1) I agree with Marco that it is plausible that there be unexpressed genetic ‘subroutines’ that might be expressed under particular environmental stresses, leading to changes of phenotype that mimic Lamarckian evolution.
(2) I agree with Marco that is plausible that there be control mechanisms that under the pressure of particular environmental stresses allow increased levels of mutation in particular ‘subroutines’ that correlate with responses to the particular stress.
(3) I agree with Marco that a filter can plausibly be applied to these randomly mutated subroutines to allow only some to be expressed.
(4) I further agree with Marco that gametes containing selectively expressed altered sub-routines could possibly be tested with respect to some parameter *correlated* with fitness to survive a particular environmental stress, before they are used.
So what are we still arguing about?
I think all this amounts to a plausible model for something which is tolerably close to Lamarckian evolution, but does not amount to *directed* mutation towards a phenotype that will provide better fitness under specific environmental conditions. And Marco still seems to be pressing for classical *directed* mutations. He says:
However this really opens up a door to: a theory that postulates selective 'good' mutations in the direction of better fitness ...
But it doesn’t. And 'it really opens up a door to' is not an argument. There is no physical way you can selectively mutate a particular gene such that the organism will be better able to cope with a particular condition. How can you selectively let through mutations that *will be* useful? How can an organism’s control systems have any foreknowledge of how a change in the gene will alter the fitness of the phenotype? My answer is, it can’t. To find out what the ‘program’ does, you have to ‘run the code’.
When I went to Fairfield
I did not seek my doom.
I did not hunt for goblin gold
or seek to follow fairy feet
through the dewy gloom.
When I went to Fairfield
I sought a cask of red;
I sought to buy a carton cold
and some Australian sparkling wine.
Home I went instead.
When I came to Fairfield,
to buy some liquor there,
it made my blood run cold to see
The door beneath the tavern sign
was shuttered, dark and bare.